News


bitop will present its latest innovations at the Vitafoods 2018 in Geneva

Dortmund, 03.05.2018: The original manufacturer of Ectoin® and Glycoin® natural will present its brand-new innovations on the Vitafoods 2018. Visit the bitop booth T-142 to get an exclusive sneak peek into the product developments and innovation pipeline. This year, Pulmonology, Ophthalmology and Animal Health are in the focus.

The SoftBreezer® combines the power of bitops Ectoin® Inhalation Solution with the device know-how of Ursatec. The portable inhaler will be released soon with a randomized clinical trial studying air pollution-induced lung disease.

The Ophthalmology line will be upgraded by the Ectoin® Eye Spray on the basis of colloids. This worldwide innovation uses colloids as a carrier system for the substance Ectoin®. A clinical trial is currently running to prove the superiority of Ectoin® Eye Spray over the German market leader.

bitop is pleased to present its Animal Health and Care portfolio that consists of two new product lines: Ectoin® pet and Ectoin® equi. The ranges have been specifically developed for man´s best friends: dogs, cats, small pets as well as horses, ponies and donkeys. All products are developed in Germany and manufactured in accordance with highest quality standards, following ISO13485.

Interested parties will get the chance to inform themselves about those pioneer products and the opportunity to get the distribution license in every country worldwide. Contact us to arrange a meeting or just come by our booth.


New USA Patent in force for the use of Glycoin® natural

Dortmund, 07.03.2018: The protection of its intellectual property is one of the main factors for the success of bitop’s Extremolytes “Made in Germany”. Therefore, the company is proud to announce that the United States of America granted another patent. Years of research have gone into the “Use of Glucosylglycerol” which is now protected in the USA. Glucosylglycerol is the chemical name for our one-of-a-kind Extremolyte Glycoin ® natural. It can be found in the resurrection plant Myrothamnus flabellifolia in the desert of South Africa. The Extremolyte protects this unique plant during drought periods from death through dehydration. This protective characteristic can be transferred to human skin where the multifunctional anti-aging and cell-boosting active ingredient targets tired, stressed or mature skin. The natural stress protection molecule revitalizes, stimulates and improves slowed or impaired cell functions to re-activate the power and appearance of youthful skin.

Abstract from the patent:

The invention relates to the use of glucosylglycerol or its esters with a view to increasing the expression of cell protective enzymes for the protection and stabilization of human skin and/or mucous membranes. It has been demonstrated that glucosylglycerol plays an effective role in the stimulation and activation of cell protective enzymes. It is thus possible in this manner to protect human skin cells effectively against damaging external influences.

If you are interested in our white label cosmetics with Glycoin® natural, or in purchasing our Extremolytes as raw material for your own cosmetic products, please contact the business development team: bd@bitop.de


bitop has moved to brand-new office building and production facility

Dortmund, 21.02.2018 : Hello Dortmund! Goodbye Witten. We have arrived in our new office building and production facility located at the “PHOENIX West” area - an innovative technology and service location in Dortmund.

With a 1.520 m² state-of-the-art production hall and 1.250 m² office and laboratory space, bitop will be able to significantly expand its production capacity for Ectoin® and other extremolytes.

From now on, our office address is:

bitop AG
Carlo-Schmid-Allee 5
44263 Dortmund, Germany
Phone: +49 231 98 77 44 0
Email: info@bitop.de


Please note that the old company address is still active and valid for R&D and manufacturing:
Stockumer Straße 28, 58453 Witten/Germany


Merry Christmas and a Happy New Year!

Witten, 11.12.2017 - bitop would like to thank all customers and partners for the successful relationship in the past year. We wish you a joyful holiday season and a good start to an even more successful year in 2018.

Please consider that we close our office from 23.12.2017 to 01.01.2018.


bitop AG receives EFRE.NRW funding for investment in efficient production technology

Witten, 23.11.2017 - In the course of the move to its new company site, bitop builds a brand-new plant for the biotechnological production of high-quality protective substances. These extremolytes (e.g. Ectoin®) are manufactured for the use in medical devices, cosmetics and animal health products. A major focus in the development of the plant laid in the search for alternative production technologies and the improvement of its efficiency regarding resources and energy consumption.

“We are proud and feel honored to receive the funding. Ever since our founding, bitop stands for innovation and well-being. We aim to follow these values in every aspect of our business and are glad to do our part to protect the environment” states Daniel J. Berger, CEO.

A substantial efficiency-improvement has been reached along the complete production process from the concentration and purification to the raw product. The introduction of up-to-date membrane processes enables bitop to significantly reduce purification wastage, use of auxiliary materials and energy consumption. A closed process management protects operators from emission and makes air exchanges during the production redundant. Partner of bitop in the development, planning and realization of the plant is the OSMO Membrane Systems GmbH, a specialist for innovative solutions in the field of various filtration and reverse osmosis processes in the chemical industry.

The investment in innovative, resource- and energy-efficient production technology is substantially supported by grants from the state of North Rhine-Westphalia using funds from the European Regional Development Fund (EFRE) 2014 - 2020. The funding was granted by the State Office for Nature Environment and Consumer Protection North Rhine-Westphalia (LANUV). The decision to award funding by the LANUV was made in a competitive procedure; the submitted projects were assessed and selected by a panel of experts. In the systematic evaluation of potential for the improvement of resource and energy efficiency, bitop AG received valuable support from the Effizienz Agentur NRW - the competence center for resource efficiency in NRW.



Extremolyte – Seminar: successful 2nd edition in Taiwan.

Witten, 09.11.2017 - In cooperation with our Taiwanese distribution partner DKSH we hosted our second edition of Extremolytes – Seminar 2017 for our customers in Kaohsiung (6.11.17) and Taipei (7.11.17). bitop presented new study data about anti-pollution and blue light protection with our multifunctional “wow-active” Ectoin® and demonstrated the power of revitalization with energizing Glycoin® natural for mature and tired skin.

Thank you Taiwan for your hospitality and interest in our products.

We are looking forward to coming back in 2018!


Second edition of bitop`s technical customer workshop “Extremolyte's secret” in Taiwan

Witten, 25.10.2017 - In June 2017, we hosted our first customer workshop in Taipei, Taiwan in cooperation with our Taiwanese distribution partner DKSH. Due to the big success, bitop and DKSH organized two other events on November 6th and 7th in Taipei and Kaohsiung. The participants will have the chance to explore the world of extremolytes and get a deeper insight in our cosmetic active ingredients Ectoin® and Glycoin® natural.

We will present and discuss the mode of action, efficacy data, applications as well as the hot market and consumer trends “anti-pollution” and “blue light protection”. bitop will share the latest scientific findings – it will be exciting!

We are looking forward to these special events.


Doetsch Grether launches neo-angin® protect Spray with Ectoin ®


bitop is proud to announce that it’s Swiss partner Doetsch Grether successfully launched the Ectoin® Mouth and Throat Spray under it’s well established neo-angin brand.

The spray is perfectly designed to precisely prevent and treat inflammation in mouth and throat. Once applied, it forms a protective layer on the sensitive membranes in the oral cavity: The Ectoin® Hydro-Complex. This shield helps to reduce inflammation which can appear due to mouth dryness or during a common cold. The product provides fast and local relieve for the painfully inflamed oral mucosa. Additionally, it can reduce bacterial ingression and stabilize the mucosal barrier.

A comparative study proved superior efficacy in treating acute pharyngitis and/ or laryngitis compared to mineral salt pastilles (Emser® pastilles).

The spray contains 100% natural ingredients. It is free from preservatives and dyes, vegan and sugar-free.

If you are interested in in-licensing this innovative product outside of Switzerland, please contact our business development team: bd@bitop.de.


In-cosmetics north america 11-12 October 2017

Witten, 16.10.2017 - For the second time, bitop exhibited at in-cosmetics north america. We presented our all-natural, COSMOS and Natrue approved active ingredients Ectoin® and Glycoin® natural to the cosmetics industry. Trending topics were the blue-light protection and anti-pollution efficacy of our “wow-active” Ectoin® and the stimulating activity of our powerful cell-energizer Glycoin® natural.

Thank you New York! We are looking forward to come back in 2018.


bitop broadens its eye care portfolio with a new Ectoin® ophthalmology range

Witten, 04.10.2017 - Besides its well-established Ectoin®-containing eye drops, bitop currently broadens its ophthalmology product range with different additional Ectoin®- and Glycoin® natural containing products. These new product developments are designed to prevent or treat ophthalmological diseases such as dry eye syndrome, allergic conjunctivitis, eczema and blepharitis and will fulfill various customer preferences with regards to application forms.

The range extension contains four innovative Ectoin® formulations for the eye:

  • Ectoin® Eye Serum for treatment of blepharitis
  • Ectoin® Lid Wipes for treatment of dry, irritated and inflamed eye-lids
  • Ectoin® Eye Spray for treatment of dry, tired, irritated and inflamed eyes
  • Ectoin® Eye Gel for treatment of dry, tired, irritated and inflamed eyes

Ectoin® based products have already proven their efficacy and excellent tolerability for application in the eye in several clinical studies and in different markets. The new products will line-up in bitop’s established Ectoin® eye product portfolio which consists of eye drops in ampoules or multi-dose units for dry or allergic eyes. Ectoin® containing products are suitable for very sensitive patients and children and do not contain preservatives, where applicable.

Contact our business development team to get to know more about the products and to discuss your license opportunities for our ophthalmology range: bd@bitop.de.


bitop strengthens derma-expertise for the extension of its Ectoin® medical skin care range

Witten, 15.09.2017 - bitop has recently dedicated its research capacities to the development of special formulations for the treatment and prevention of different serious skin diseases. Currently, bitop develops products for the treatment of:

  • Hemorrhoids disorders
  • Vaginal dryness
  • Rosacea
  • Acne
  • Wounds
  • Scars

Each of these highly specialized products will have a unique Extremolyte-containing formulation with beneficial supportive ingredients. They extend the existing skin care range with Ectoin® for the treatment and prevention of inflammatory skin diseases.

Contact our business development team to get to know more about the products and to discuss your license opportunities for our medical skin care range: bd@bitop.de.


Biohorma launches Ectoin® Ear Spray in the Netherlands

Witten, 18.08.2017 - bitop is proud to announce that its new Ectoin®-containing Ear Spray has recently been launched by the successful Dutch partner Biohorma. Biohorma placed its product “Oorspray Oorsmeer” under the well-known “A. Vogel” brand.

The product is designed to treat symptoms of non-infectious inflammations in the outer ear, for prevention of otitis externa and earwax plugs, and for eased clearing of the outer ear canal.

Dr. Uwe Sonnemann, ENT specialist from Hamburg (Germany) explains why he sees a huge market potential for the product:

“Ear itching severely impairs daily life of numerous people worldwide. Reasons for ear itching are diverse and treatment is often challenging since products that contain pharmaceutical drugs have well-known side effects while natural ear sprays are often not effective enough. bitop has developed an ear spray that fills this gap in the market. Their product “Ectoin® Ear Spray” proved its efficacy in reducing ear itching and other symptoms of inflammatory irritations of the outer ear canal on a safe, natural and very effective way. I feel very confident that the product will successfully establish itself on the OTC market within a short time.”

If you would like to be part of the success story of this innovative product, contact our business development team for more information: bd@bitop.de.


Brand-new Ectoin® Lozenges formulation expands bitop’s successful cough and cold product line

Witten, 16.07.2017 - The unique formulation “Ectoin® Lozenges HC + Salt” contributes to the existing Lozenges range for the treatment and prevention of common cold symptoms, dry mouth and throat, and hoarseness due to voice overuse.

The innovative formulation differentiates itself from the existing Ectoin® Lozenges by the additional ingredient sea salt. Sea salt helps to dissolve thick and compact mucous. Furthermore it increases the saliva production which results in a hydrated epithelia and symptom reduction while suffering from a cold. Strong claims can be used to position the product successfully on the market:

  • Reduces inflammations of the mucous membranes in mouth and throat
  • Relieves hoarseness, sore throat, or pain on swallowing
  • Stabilizes the mucous membranes
  • Reduces the danger of bacterial or viral infection in the mouth and throat
  • Reduces and prevents irritations of the mucous membranes such as voice fatigue, tickly throat, or dryness caused by voice overuse, allergens or dry air resulting from e.g. heating, cold, air conditioning, or smoke
  • Dissolves thick and compact mucus
  • Forms a protective shield called “Ectoin® Hydro Complex” on mucous membranes in mouth and throat without leaving a slimy feeling
  • Hydrates dry and irritated epithelia and supports their regeneration
  • Increases the saliva production
  • Effects based on 100% natural ingredients

“Ectoin® Lozenges HC + Salt” lozenges are preservative- and sugar-free – like all bitop formulations. They combine the positive effects of natural sea salt and Ectoin®, a cell-protective molecule with inflammation-reducing and membrane-stabilizing properties. The new Lozenges have a pleasant honey-lemon flavor with a light salty note.

Contact our business development team to discuss your license opportunities for our cough & cold range: bd@bitop.de


Our cosmetic active ingredient Glycoin® natural won the 'Ringier Technology Innovation Award'!

Glycoin® natural was honored in the ‘effective ingredients: anti-aging’ category at the Ringier Technology Innovation Awards 2017 sponsored by happi China magazine. Winners were announced at the awards ceremony on June 22, 2017 in Shanghai, China.

We are proud to show you our award certificate.

Meet us at

Suppliers' Day in New York,
15-16 May 2018

Meet us in New York at the Suppliers' Day at Stand 109.


Vitafoods Europe in Geneva,
15-17 May 2018

Meet us in Geneva at the Vitafoods Europe at Stand T142.

Past Fairs

in-cosmetics global in Amsterdam,
17-19 April 2018

Meet us in Amsterdam at the in-cosmetics global at Stand H335.


Personal Care and Homecare Ingredients (PCHi) in Shanghai,
19-21 March 2018

Meet us in Shanghai at the PCHi at Stand IF37.



3rd OTC Toolbox/PLG OTC Conference and Networking Event,
1-2 March 2018

Meet us in London at the OTC Conference in the Hilton London Tower Bridge.


Making Cosmetics & Formula Cosmetics in Milan,
28-29 November 2017

Meet us in Milan at Making Cosmetics & Formula Cosmetics at URAI Spa Stand 349. Join our presentation "Global anti-pollution, skin protection and repair with clinically proven efficacy: Ectoin®" on 28 November - 15:00-15:20.

in-cosmetics asia in Bangkok,
31 October - 2 November 2017

Meet us in Bangkok at the in-cosmetics asia at DKSH Booth D10.


CPhI in Frankfurt,
24-26 October 2017

Meet us in Frankfurt at the CPhI Worldwide for pharmaceutical ingredients at Stand 90B01.


SEPAWA CONGRESS in Berlin,
18-20 October 2017

Meet us in Berlin at the SEPAWA CONGRESS at Stand E722.


in-cosmetics north america in NYC,
11-12 October 2017

Meet us in New York City for the second edition of the in-cosmetics in North America at Stand E56.


in-cosmetics Korea in Seoul,
20-22 June 2017

Meet us in Seoul for the third edition of the in-cosmetics in Korea.