Eye Care

Ectoin® Sicca Eye Drops

Protection from dry and itchy eyes

Claims

Eye drops for treatment and prevention of dry eye symptoms.

  • Moisten dry eyes and prevent further dehydration.
  • Reduce inflammations caused by irritated or dry conjunctiva.
  • Alleviate symptoms of dry eyes such as burning, dryness, itching, etc.
  • Support the regeneration process of dry and irritated conjunctivas.
  • Suitable for preventive use.
  • Protect ocular cells from hyperosmolarity.
  • Stabilize the lipid layer of the tear film.
  • Suitable for sensitive eyes and contact lens wearers.

Ingredients

Ectoin®, Hydroxyethyl Cellulose, Sorbitol, Water, Citrate Buffer.

Suitable for

Newborn, infants, children, adolescents and adults.

Dosage Forms

0.5 ml solution in single-dose ampoules or 10 ml in a multidose dropper (OSD)

 Study Overview

Dwivedi et al., 20141; Dwivedi et al., 20142;
Drozhzhyna et al., 20173; Veselovska et al., 20164

Status (EU): Medical Device

Ectoin® Sicca Eye Drops + HA 0.2%

Tear film stabilization, itch reduction and moistening of dry eyes

Claims

Eye drops for treatment and prevention of dry eye symptoms.

  • Moisten dry and irritated eyes.
  • Reduce burning and itching.
  • Stabilize the lipid layer of the tear film and reduce further dehydration.
  • Protect ocular cells from hyperosmolarity.
  • Aid cell regeneration.
  • Suitable for contact lens wearers.
  • Also effective as a preventive treatment.

Ingredients

Ectoin®, Sodium Hyaluronate, Sodium Chloride, Water, Citrate Buffer.

Suitable for

Newborn, infants, children, adolescents and adults.

Dosage Forms

0.35 ml solution in single-dose ampoules or 10 ml in a multidose dropper (3K or OSD)

 Study Overview

Dwivedi et al., 20141; Dwivedi et al., 20142;
Drozhzhyna et al., 20173; Veselovska et al., 20164

Status (EU): Medical Device

Ectoin® Healing Aid Eye Drops

Reduce inflammation and support healing after eye injuries or surgeries for a faster recovery of a clear vision

Claims

Eye Drops for the treatment of inflammatory diseases of the corneal and ocular surface.

  • Reduce inflammation of the conjunctiva/eye.
  • Quick symptoms reduction like itching, tearing, and irritation within 30 seconds.
  • Alleviate symptoms such as burning, dryness, itching, redness, foreign body sensation, etc.
  • Moisturize dry eyes and prevents further dehydration.
  • Superior decrease of inflammatory mediators due to cell stabilization of Ectoin Hydro Complex.
  • Support wound healing after ocular surgeries and/or injuries of the eyes.
  • Support faster epithelization in the early postoperative period.
  • Transparency of cornea is regained faster after an eye injury or surgery.
  • Improve cell regeneration.
  • Imbalanced tear production is completely restored to a normal level and tear film stabilized.
  • Proven efficacy also in combination with antibiotic, antiseptic, or other anti-inflammatory treatment.
  • Suitable for all ages, sensitive eyes, and wearers of contact lenses.

 

Ingredients

Ectoin®, Sodium Chloride, Hydroxyethyl Cellulose, Citrate Buffer, Water.

Suitable for

Infants, Children, Adolescents and Adults.

Dosage Forms

0.5 ml solution in single-dose ampoules

 Study Overview

Ustimenko et al., 20175; Vitovskaya et al., 20186; Serdyuk et al., 20177

Status (EU): Medical Device

 

 

Ectoin® Eye Gel

Higher viscosity enabling strong protection, effective healing support, and lasting symptom relief: Due to longer retention time, Ectoin® can unfold its anti-inflammatory and moisturizing effect even more.

Claims

Eye gel drops for the treatment and prevention of dry, irritated, and inflamed eyes, e.g. allergic conjunctivitis or dry eye syndrome or other inflammatory diseases of the corneal and ocular surface.

Prevention

  • Effective as a preventive treatment
  • Protect against harmful influences of allergens
  • Reduce allergen-induced inflammation of the conjunctiva
  • Prevents eye irritations and forms a protective layer

Treatment

  • Calms and soothes irritated and tired eyes
  • Alleviates allergic symptoms (red, itchy, and watery eyes)
  • Intensive and longer moisturization of dry and irritated eyes due to prolonged retention time
  • Longer moisturization effect of Ectoin® due to prolonged retention time
  • Stabilizes the lipid layer of the tear film and reduce further dehydration
  • Reduces burning, itching, and foreign body sensation

Regeneration

  • Supports wound healing after ocular surgeries and/or injuries of the eyes
  • Supports the regeneration process of irritated and sensitive conjunctiva

 

Ingredients

Ectoin®, Hydroxyethyl Cellulose, Sodium Chloride, Citrate Buffer, Water.

Suitable for

Children, sensitives eyes, contact lens user

Dosage Forms

10 ml in a multidose dropper (OSD)

Status (EU): Medical Device

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1 Preclinical Study with Ectoin: Dwivedi M et al. Biophysical investigations of the structure and function of the tear fluid lipid layer and the effect of ectoine. Part A: Natural meibomian lipid films. Biochim Biophys Acta. 2014;1838(10):2708-15.

2 Preclinical Study with Ectoin: Dwivedi M et al. Biophysical investigations of the structure and function of the tear fluid lipid layer and the effect of ectoine. Part B: Artificial lipid films. Biochim Biophys Acta. 2014;1838(10):2716-27.

3 Clinical Study with medical device Ectoin Allergy Eye Drops: Drozhzhyna et al. New eye drops - "Eye-t Ectoin Pro" for the treatment of allergic conjunctivitis 2017. Online Publication: https://farmaplant.ua/novye-glaznye-kapli-eyet-ektoin-pro-2-dlja-lechenija-allergicheskogo-konjunktivita/a-71.html Accessed on Sep 12th 2017

4 Clinical Study with medical device Ectoin Sicca Eye Drops: Veselovska et al. Results of dry eye syndrome treatment during corrective contact lens usage. 2016. Online Publication: https://farmaplant.ua/rezultaty-lechenija-sindroma-suhogo-glaza-v-kontaktnoj-korrekcii/a-67.html Accessed on Mar 11th 2020

5 Clinical Study with medical device Ectoin Allergy Eye Drops: Ustimenko et al. Efficiency of application of tear substitutes in early postoperative period in patients with advanced keratoconus. 25-26th May 2017. Abstract to oral presentation at ophthalmologists congress “Filatov Memorial Lectures 2017” Odessa, Ukraine.
 

6 Clinical Study with medical device Ectoin Sicca Eye Drops: Vitovskaya et al. Pecularities of diagnostics and treatment of secondary dry eye syndrome in front surgery pathology. EYE-t Ektoin 0.5 %. 2018. Online Publication: https://farmaplant.ua/osobennosti-diagnostiki-i-lechenija-vtorichnogo-sindroma-suhogo-glaza-pri-patologii-perednej-poverhnosti-glaznogo-jabloka/a-76.html Accessed on Mar 11th 2020

7 Clinical Study with medical device Ectoin Allergy Eye Drops: Serdyuk et al. The effect of ectoine on traumatic uveitis course in children. 2017. Int Sci-Pract J Ophthalmol No. 6 2017 УДК 617.7-001-002-053.2-08:615.457